Fig. 7: Adenovirus 26 Entering a Host Cell

1. Fibers on adenovirus 26 adsorb to receptor molecules on a host cell.
2. The virus is taken into the host cell by endocytosis and placed in an endosome.
3. The endosomal membrane is broken down releasing the virus particle.
4. The virus particle travels to the nucleus of the host cell and disassembles.
5. The viral DNA enters the nucleus of the host cell.
6. The viral gene coding for spike protein is transcribed into viral mRNA.
7.The viral mRNA leaves the nucleus where host cell ribosomes translate it into SARS-CoV-2 spike proteins..

Illustration of Adenovirus 26 (Vaccine Virus) Entering a Host Cells .jpg by Gary E. Kaiser, Ph.D.
Professor of Microbiology, The Community College of Baltimore County, Catonsville Campus
This work is licensed under a Creative Commons Attribution 4.0 International License.
Based on a work at https://cwoer.ccbcmd.edu/science/microbiology/index_gos.html.

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Last updated: Feb., 2021
Please send comments and inquiries to Dr. Gary Kaiser